samtools view problem in HyDRA

Question

[nadinezakkak]

I downloaded quasitools from github and I tried to run HyDRA for HIV genotyping, but I am getting the following error when trying to run it:

Error: samtools view returned the following output:
b'dyld: Library not loaded: @rpath/libcrypto.1.0.0.dylib
Referenced from: /PathToAnaconda/samtools\n  Reason: image not found'

I read somewhere that uninstalling samtools separately and reinstalling it might fix the problem, but I am still getting the same issue.

It would be great if anyone has any advice on how to fix this problem.

Thank you

[GenoMax]

Is HyDRA available via conda? If it is, the best option would be to install that and samtools using conda.

[nadinezakkak]

Yes it is. Yes when I tried reinstalling samtools, I did so using conda.

Answer 1

[GenoMax]

Can you create a new environment and try?

conda create -n newenv samtools hydra

[nadinezakkak]

This worked. Thank you!!