Calculate matrix of distances between sequences
Can someone help me with this question ?
For exercise 1 use pen and paper.
Consider the following multiple sequence alignment from a set of four sequences:
S1: A-CATATC-AT- S2: A-GATATT-AG- S3: AACAGATC-T-- S4: G-CAT--CGATT
- Calculate the distance matrix. Assume the metric distance as the number of distinct characters in pairwise alignment (assume the pairwise alignment given by the multiple sequence alignment).
I really dont know how this is calculated manually
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Sorry, this is now closed. You could have at least tried to conceal the fact that this is an exam question. The expectation is that you will do some research and come up with an answer through that.