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Tajima's D test applied to tandemly repeated genes

Tajima's D test is normally used to test for evolutive contraints on a DNA sequence by analyzing population samples. In the following article, it is used to test paralogous sequences of a large array of repeated genes. There are no population variants analyzed. I wonder wether such an extrapolation of the Tajima's D test is correct.

PMID: 24945811

Thanks for advices!

alignment sequence snp
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written by jaer.wees • jaer.wees

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