Thank you. I have moved this to an answer.
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Kevin Blighe
q-value > 1 in STAMP
Hi all,
I am using STAMP, a powerful tool in statistics, to determine which bacteria is differential in my sample. "BH" was adopted to correct the p-value, but the q-value is > 1. It is, in theory, impossible. Does anyone know what happens? Thanks very much.
genus p-values p-values (corrected)
g__Collinsella 0.931588858 1.054628896
g__Oscillibacter 0.914789867 1.05552677
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zhangdengwei
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thanks. I have got a reply from the developer. STAMP uses the following definition to calculate BH q-value:
q-value = p-value*(total number of hypotheses tested)/(rank of the p-value)
These are not restricted to be <1.0.
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In case there is no response, you may consider contacting the developer. E-mail available here: https://beikolab.cs.dal.ca/software/STAMP_FAQs