This is a test version of Biostars. For the public version, visit https://www.biostars.org.
How to interpret logistic interaction results from plink2 output?

Hi,

I've run gwas logistic regression on UKBio data using plink2 geneXenvironment interaction with HB category. The results output look like this for example:

CHROM  POS   ID              REF  ALT  A1  FIRTH?  TEST          OBS_CT  OR    LOG(OR)_SE   Z_STAT  P      ERRCODE

22      160...       rs587XX     C       A       A       N       ADD             2...         0.21   4.36                 -0.351   0.72        
22      160...       rs587XX     C       A       A       N       HBcat           2...         3.87   0.06                  21.27   1.86e-100    
22      160...       rs587XX     C       A       A       N       ADDxHBcat  2...        1.30    2.38                  0.11    0.911

How can I combine all of the interaction terms and main SNP effects to get HB-category-specific ORs for each SNP? Can I even do it with the output given or do I need the beta coefficients?

Any help is appreciated,

AJ

snp plink gwas interaction logistic

Please elaborate some more on what you want to do, and please show the command(s) that you used to generate the current output. Please elaborate on "HB-category-specific ORs"

0 answers

No answers yet.

Log in to answer this question.