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How to do a PCA plot on the exome data using different library kits?

Hi,

I have around 1000 exome data (fastq, bam, vcf). I want to a PCA plot on the exome data using different library kits for the QC step. I would expect the PCA plots showing clusters of samples using different library kits.

May I know any suggestion? Any software package can help? Use BAM or VCF file?

Thanks a lot!

Regards, Mullin

exome pca library-kit exome sequencing

Ideas for what? Please open a new question if you need help.

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