Hi,
After calling somatic variants from tumor samples against normal ones, we still get a lot of true somatic variants that require variants-drug interpretations.
CKB database offers lots of high level annotations, as well as those pre-clinic ones, which can largely provide comprehensive actionable drug-able information.
However, CKB database did not provide API service, since its commercial mode.
Is there any similar comprehensive database, since our aim is to provide/integrate API/WEB service to the workflow.
--PS Other databases listed in https://github.com/seandavi/awesome-cancer-variant-databases have been tried, but none of them perform as CKB.
•
written
by
J.F.Jiang
1 answer
You could try Open Targets, from Denise & Co. ( https://www.opentargets.org/ / https://www.targetvalidation.org/ ).
Their related publications:
Open Targets Platform: new developments and updates two years on
Open Targets: a platform for therapeutic target identification and validation
Kevin
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