miR155HG is significantly up-regulated in EBV-transformed lymphocytes
How to understand miR155HG is significantly up-regulated in EBV-transformed lymphocytes?
Thanks.
Solved: EBV modulates host miR-155 expression, which is essential for the growth of EBV-infected B cells. EBV-infected cells have increased expression of miR-155 thereby disturbing the equilibrium of expression for genes regulating transcription in those cells
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Did you do any literature research? https://en.wikipedia.org/wiki/MiR-155
Search for EBV, the Wiki article even mentions it in the EBV context and gives link to scientific literature.
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Did you discuss this finding with your supervisor / PI / collaborating scientist in virology esp on EBVS? Shicheng Guo