BWA-MEM rather than bowtie2 in UKBB exome-sequencing alignment

Hi All,

Who knows why UKBB applied BWA-MEM rather than bowtie2 for the first 50,000 UKBB exome-sequencing alignment?

Thanks.

exome-sequencing

• 1,212 views • link

updated 6.5 years ago by Biostar

• written 6.7 years ago by Shicheng Guo

Were they considering Bowtie2?

I don't know how UKBB chose their pipeline, but most exome sequencing projects (for example, TCGA or gnomAD) use BWA, so it's not a surprising choice.

• 0 views • link

written 6.7 years ago by igor

0 answers

No answers yet.

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