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Download EC number tree

I want to download for the full EC number tree (with all level) and can't find it. My purpose is to assign all levels for a list of enzymes (in example for 1.1.1.1 not just to tell that it alcohol dehydrogenase but also to tell that it is oxidoreductase (class 1), Acting on the CH-OH group of donors (subclass 1.1) and so on...) Just for clarification- I'm interested in the annotations (in each level) of each enzyme, not in the sequences.

gene
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updated by GenoMax GenoMax • written by biobiu biobiu

Thanks! I'm not interested in the sequences but in the enzyme annotations.

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written by biobiu biobiu

1 answer

UPDATE: This page may be simpler to use. No parsing needed.

Just classes.

You can download this file from SwissProt/ExPASY ENZYME database. You can then parse ID,DE,AN,CC lines to get the information you want.

ID   1.1.1.1
DE   Alcohol dehydrogenase.
AN   Aldehyde reductase.
CA   (1) A primary alcohol + NAD(+) = an aldehyde + NADH.
CA   (2) A secondary alcohol + NAD(+) = a ketone + NADH.
CF   Zn(2+) or Fe cation.
CC   -!- Acts on primary or secondary alcohols or hemi-acetals with very broad
CC       specificity; however the enzyme oxidizes methanol much more poorly
CC       than ethanol.
CC   -!- The animal, but not the yeast, enzyme acts also on cyclic secondary
CC       alcohols.
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written by GenoMax GenoMax

Thanks! The only thing is missing now is the classification of the upper levels (like Class 1 - oxydoreductase)

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written by biobiu biobiu

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