Since deconstructSigs has been removed from CRAN, as well as some of its dependencies. We have trouble installing this package, mainly to find the write …

Hello, I'm doing some research in bladder cancer and i have a dataset of genotyped data so i have GWAS summary statistics from 2 GWAS. …

Hello, I want to perform colocalization analysis between an eqtl- and a GWAS-dataset. For this I want to use the `coloc.abf` function from [R coloc …

Hi, I'm looking for a project in Bioinformatics that I can do on my own using data available online. I've been looking for an internship …

I have MS/MS data that I searched with MS-GF+. Unfortunately, MS-GF+ doesn't do protein inference, so I have a list of peptides in .mzid format. …

I am looking for open source tools that can infer mutations from tumor sample without paired normal sample. I understand you can use tools like …

There are many softwares that can call tumor normal pairs easily. However, in a real clinical setting, we only have tumor sample, and likely on …

So what is the best practice for GWAS RNA-seq quantification? GWAS does not compare different gene expression in each sample. However, it's very important that …

Hi, We are planing to call copy numbers from SNP6 array from tumor and normal samples. I know there are many tools normal sample genotyping. …

<p>Something like query SNP against, say, splicing junctions, or in general, overlapping ranges against genomic and epigenetic features. </p> <p>I know to use GRanges, but …