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GO slimming to specific parent term

GO slimming allows you to trace back a child GO term to a broader, parent term. Is there a package (preferably R) that allows you to choose which parent you want to trace back to? i.e. For a set of GO IDs, I want to find all the ones that fall under the umbrella of, for example, "transcription regulator activity".

It would be most preferable to find a standalone program, rather than website, to do this (but I'll take anything in the end).

Thanks!

go gene ontology slimming parent child

2 answers

GSEABase has a function for this that might be helpful.

Thanks that looks perfect! I'll give it a try :)

The Bioconductor GO.db package allows you to work with the Gene Ontology graph.

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