Hello,

Does any one know a of a tool that could provide me mutational network occurrence in cancer samples? For example: If I have all the mutations from breast caner I would like to get all the combinations of co-occurring mutations observed in those patients and their frequencies across patients. For example the desired output would look like this:

Mutational combinations:

HRAS,TP53, CDKN1A

HRAS,TP53, CDKN1A,EGFR

EGFR, CDN2A, NRAS,ALK,PTEN,PI3K

TP53, NRAS, STK11, PTEN,MDM2,CDKN1A2, GADD45A,PUMA,BAX

Thank you for your help