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Convert physical positions from Hg18 to Hg19

Hello, I have a file like this one (but with thousands of rows):

A B C D
994 437756 1 437756
988 204037 1 641793
982 89637 1 731430
976 48461 1 779891
970 30768 1 810659
964 21334 1 831993

A: score
B: size of the genomic region in base pairs
C: chromosome
D: physical position (hg18 assembly)

I'd like to convert physical positions from hg18 to hg19. Is there a simple way to do this based just in physical positions?

liftover

1 answer

You should convert this file to the BED format and then read and/or follow

Converting Genome Coordinates From One Genome Version To Another (Ucsc Liftover, Ncbi Remap, Ensembl Api)

Conversion Between Hg18 And Hg19

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