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Mutual Information in Nucleic Acid Seqs

Hi all,

I am looking for a software tool that would be able to do a mutual information analysis on an alignment of DNA sequences from an HTS sequencing (~ 100K unique seqs) to see which NTs might be interacting. I found MatrixPlot and CorreLogo, but they both seem to be able to process only two seqs at a time. Do you guys have any suggestions of what I could use? Many thanks!

Katka

next-gen

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