Tools to access variation of ploidy at certain genomic loci using WES

Question

[Rahul Sharma]

Hi all,

I am checking for ploidy level variations after endomitosis among diseased and control samples using WES data at certain chromosome loci. I could not find any specific tool for such an analysis. There are tools like nQuire and ploidyNGS for checking the ploidy levels on whole genomes. Would be great if anyone could suggest any such tool or method for this kind of analysis?