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You mean genes encoding for transcription factors enriched in your differentially-expressed genes? If not, please elaborate.
Yes - Tools to detect genes encoding for transcription factors from microarray/RNAseq data?
It's still not really clear what you want. Why can't you just do a standard differential expression analysis and pull out transcription factor genes from a list afterwards? Or are you trying to actually show that transcription factor genes are enriched in your differentially expressed gene set, as ATpoint said?