My SV caller has been Manta, my script does annotation on Manta. What is your SV caller?
How to annotate structural variants in VCF with esv/nsv identifiers
Hi!
I'm struggling with finding a way to annotate a manta structural variants VCF output with SV regions identifiers from DGV/dbVAR (esv/nsv). Direct annotation based on the exact reported chromosomal positions certainly would not work as most of the structural variants have imprecise start-end locations. I did not manage to find the desired functionality in VEP, snpeff, annovar and loads of other tools reported elsewhere. I would appreciate any information on this issue.
Thanks! Kirill
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I have not used though but hope helps
https://github.com/brentp/vcfanno
Thank you. Actually, I've come across this tool while googling but did not manage to comprehend its ability to do so. Now I do. I'll try it and post the result.
vcfanno works very well, I can recommend it.
if you still need help I can help you
Can you please help on this ?