How to deal with wig files separate bu watson and crick strand
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5.3 years ago
Lila M ★ 1.2k

Hi everybody, I downloaded some wig files (GRO-seq data) that contains genomic read coverage (merging the two lanes of the same sample). Separate files were created for the Crick and Watson strands (sample1_strand-rep1_lane1.wig, sample1_strand+rep1_lane1.wig ,sample1_strand-rep1_lane2.wig, sample1_strand+rep1_lane2.wig), but I would like to get one single file in order to get the counts for each gene and create some TSS profiles. I am a bit stuck because I don't know if there is a proper way to merge the wig files by strand or it it should be done in another way. Any suggestions? Thanks

wig GROseq TSSprofile deepTools • 1.0k views
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