how can I extract group or modules from a huge number of intractions between gene-TF or gene-miRNA?

Question

[Calangoa]

Hi, would you please anyone explain how can I extract group or modules from a huge number of intractions between gene-TF or gene-miRNA? I mean, I have a network with more than 100,000 intractions between TFs and genes or miRNA-genes and it is a big network, I only want nodes with highest number of interactions to reduce the number of interaction to a tenth or a percent.