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how to compere Gene ontology for some data set from micorraray with differentiallay expressed genes

Hi there, I have a question, how to compere Gene ontology for some data set from micorraray with differentiallay expressed genes? I know there are different option for annotation individual sets like BinGO, DAVID and etc but I want to compare GO for a set of DEGs. Is Hierarchical clustering a good chose?

Any suggestion would be helpful

Thanks in advance

gene go

1 answer

For something like this, GO enrichment is really what you want. There are lots of tools that can do that, including several R packages like enrichR and clusterProfiler, which is a personal fave for the figures it can generate.

Thanks Jared for your helpful answer

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