FASTA to Gene Names (Is BLAST the best option)
Dealing with an unannotated genome. I have the sequences of genes I'm interested in knowing the names of (in fasta format.) The idea was to simply BLAST them against a species that we believe is closely related. However, is there any other options or software that might be best suited?
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Is this a pro- or eukaryotic genome. With prokaryotic genomes
prokka(https://github.com/tseemann/prokka ) is what people recommend for annotation of new genomes.You could simply
blast(do it at protein level to get better matches) against a closely related genome if one is available.Blasting will not give the names of the genes, it will give you the names of the most similar genes in a database. Have in mind that the names of those genes in the database may have been themselves derived from blast searches.