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more transcriptional factors involved lead to quick or slow phenotype transition?

As the title says. I have found that one phenotype transition has more TF genes involved while the reverse process need less TFs. Also, these two processes have different rates of transition. So, I wonder if there was any papers describing the relationship between the number of involved TFs and the rate of phenotype change?

Thank you! Pengcheng

transcriptional factors phenotype transition
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written by pengchy pengchy

There is a classical example - a sea star and a sea urchin

https://www.sciencedirect.com/science/article/pii/S0012160607013425

Caught in the evolutionary act: Precise cis-regulatory basis of difference in the organization of gene networks of sea stars and sea urchins

As far as I remember, the article describes that TFs working

at different development stages lead to different phenotypes.

I am not sure their amount matter.

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written by natasha.sernova natasha.sernova

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