When I try to install "DiffBind" on R studio, I get the erro below. I use R 3.4 and BIoconductor 3.6.

ERROR: configuration failed for package ‘curl’ * removing ‘/home/yachen/R/x86_64-pc-linux-gnu-library/3.4/curl’ * installing source package ‘openssl’ ... ** package ‘openssl’ successfully unpacked and MD5 sums checked Using PKG_CFLAGS= ------------------------- ANTICONF ERROR --------------------------- Configuration failed because openssl was not found. Try installing: * deb: libssl-dev (Debian, Ubuntu, etc) * rpm: openssl-devel (Fedora, CentOS, RHEL) * csw: libssl_dev (Solaris) * brew: openssl@1.1 (Mac OSX) If openssl is already installed, check that 'pkg-config' is in your PATH and PKG_CONFIG_PATH contains a openssl.pc file. If pkg-config is unavailable you can set INCLUDE_DIR and LIB_DIR manually via:

R CMD INSTALL --configure-vars='INCLUDE_DIR=... LIB_DIR=...'

ERROR: configuration failed for package ‘openssl’ * removing ‘/home/yachen/R/x86_64-pc-linux-gnu-library/3.4/openssl’ * installing source package ‘RMySQL’ ... ** package ‘RMySQL’ successfully unpacked and MD5 sums checked Using PKG_CFLAGS= Using PKG_LIBS=-lmysqlclient ------------------------- ANTICONF ERROR --------------------------- Configuration failed because no mysql client library was found. Try installing: * deb: libmariadbclient-dev | libmariadb-client-lgpl-dev (Debian, Ubuntu) * rpm: mariadb-connector-c-devel | mariadb-devel | mysql-devel (Fedora, CentOS, RHEL) * csw: mysql56_dev (Solaris) * brew: mariadb-connector-c (OSX) If you already have a mysql client library installed, verify that either mariadb_config or mysql_config is on your PATH. If these are unavailable you can also set INCLUDE_DIR and LIB_DIR manually via:

R CMD INSTALL --configure-vars='INCLUDE_DIR=... LIB_DIR=...'

ERROR: configuration failed for package ‘RMySQL’ * removing ‘/home/yachen/R/x86_64-pc-linux-gnu-library/3.4/RMySQL’ ERROR: dependencies ‘curl’, ‘openssl’ are not available for package ‘httr’ * removing ‘/home/yachen/R/x86_64-pc-linux-gnu-library/3.4/httr’ ERROR: dependency ‘httr’ is not available for package ‘biomaRt’ * removing ‘/home/yachen/R/x86_64-pc-linux-gnu-library/3.4/biomaRt’ ERROR: dependencies ‘RMySQL’, ‘biomaRt’ are not available for package ‘GenomicFeatures’ * removing ‘/home/yachen/R/x86_64-pc-linux-gnu-library/3.4/GenomicFeatures’ ERROR: dependency ‘GenomicFeatures’ is not available for package ‘VariantAnnotation’ * removing ‘/home/yachen/R/x86_64-pc-linux-gnu-library/3.4/VariantAnnotation’ ERROR: dependencies ‘GenomicFeatures’, ‘VariantAnnotation’ are not available for package ‘systemPipeR’ * removing ‘/home/yachen/R/x86_64-pc-linux-gnu-library/3.4/systemPipeR’ ERROR: dependency ‘systemPipeR’ is not available for package ‘DiffBind’ * removing ‘/home/yachen/R/x86_64-pc-linux-gnu-library/3.4/DiffBind’

The downloaded source packages are in ‘/tmp/Rtmp7Ysenv/downloaded_packages’ Warning messages: 1: In install.packages(pkgs = doing, lib = lib, ...) : installation of package ‘curl’ had non-zero exit status 2: In install.packages(pkgs = doing, lib = lib, ...) : installation of package ‘openssl’ had non-zero exit status 3: In install.packages(pkgs = doing, lib = lib, ...) : installation of package ‘RMySQL’ had non-zero exit status 4: In install.packages(pkgs = doing, lib = lib, ...) : installation of package ‘httr’ had non-zero exit status 5: In install.packages(pkgs = doing, lib = lib, ...) : installation of package ‘biomaRt’ had non-zero exit status 6: In install.packages(pkgs = doing, lib = lib, ...) : installation of package ‘GenomicFeatures’ had non-zero exit status 7: In install.packages(pkgs = doing, lib = lib, ...) : installation of package ‘VariantAnnotation’ had non-zero exit status 8: In install.packages(pkgs = doing, lib = lib, ...) : installation of package ‘systemPipeR’ had non-zero exit status 9: In install.packages(pkgs = doing, lib = lib, ...) : installation of package ‘DiffBind’ had non-zero exit status

install.packages("zilb") Installing package into ‘/home/yachen/R/x86_64-pc-linux-gnu-library/3.4’ (as ‘lib’ is unspecified)