Hi,

Can anyone provide me with additional helpful hints to carry the following analysis:

I want to analyse the variants of children with a cancer, where only one of the parents is available. So I do have the fastq/bam/vcf files of duos (child + one parent).

I assume one can only know the inherited variants from the available parent to the child. Also, one can phase the haplotypes of the child to get a better idea about variants in hand.(one question arises here, can we predict the haplotype of the missing parent in this case?).

Any suggestions from your side, on how can we get further useful information out of the available duos would be appreciated.