Hello Mr Locuace,

this "ID" looks to me like it describes:

• the chromosome
• position
• reference allele
• alternative allele
• reference genome

So to get the corresponding rs id, one solution is to extract the informations of the id and convert it to a vcf file. You can then annotate the ID column. There was a similar thread some time ago.

Let's start to create a vcf file. I assume you have a file id.txt which contain your id's in every line:

awk -F_ -v OFS="\t" '{print $1,$2,".",$3,$4,".",".","."}' id.txt|sort -k1,1V -k2,2g > ids.vcf

Now you can take this vcf file and annotate it with e.g. SnpSift:

java -jar SnpSift.jar annotate -id dbSNP.vcf.gz  ids.vcf > ids_annotated.vcf

Of course first you have to download the dbSnp file.

fin swimmer