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Tool: HEXplorer: Scanning splice site sequence surroundings for splice enhancing/repressing properties

Hi everbody,

I would like to shortly introduce to you the tool my working group developed, the HEXplorer.

  • Helps you to check the sequence surrounding around 5' splice sites for splice enhancing or repressing Splice Regulatory Elements (SREs) nearby.
  • Visualizes the effect of point mutations on the SRP binding properties of a given genomic sequences
  • Calculates intrinsic strength of possible splice donors or acceptors (HBS and maxent score)
  • Validated through various point mutation analysis

You can find some background for the program in this paper.

splice-site sre splicing genome

Hi,

Thanks for the tool, but the link you provided does not work. Was the tool discontinued ?

Best, Pedro

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