Tool: HEXplorer: Scanning splice site sequence surroundings for splice enhancing/repressing properties
Hi everbody,
I would like to shortly introduce to you the tool my working group developed, the HEXplorer.
- Helps you to check the sequence surrounding around 5' splice sites for splice enhancing or repressing Splice Regulatory Elements (SREs) nearby.
- Visualizes the effect of point mutations on the SRP binding properties of a given genomic sequences
- Calculates intrinsic strength of possible splice donors or acceptors (HBS and maxent score)
- Validated through various point mutation analysis
You can find some background for the program in this paper.
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Hi,
Thanks for the tool, but the link you provided does not work. Was the tool discontinued ?
Best, Pedro