Tool:HEXplorer: Scanning splice site sequence surroundings for splice enhancing/repressing properties

Question

[caggtaagtat]

Hi everbody,

I would like to shortly introduce to you the tool my working group developed, the HEXplorer.

• Helps you to check the sequence surrounding around 5' splice sites for splice enhancing or repressing Splice Regulatory Elements (SREs) nearby.
• Visualizes the effect of point mutations on the SRP binding properties of a given genomic sequences
• Calculates intrinsic strength of possible splice donors or acceptors (HBS and maxent score)
• Validated through various point mutation analysis

You can find some background for the program in this paper.

[PedroBarbosa]

Hi,

Thanks for the tool, but the link you provided does not work. Was the tool discontinued ?

Best, Pedro