mapping between gene symbol and entrez ID
Hello,
I have mapped a few gene symbols to their entrez IDs using:
library(org.Hs.eg.db)
info4gene = select(org.Hs.eg.db, symbols, c("ENTREZID"), "ALIAS")
where symbols are the gene names, such as 'NUDT10'.
As below, why are they some gene symbols can map to more than two entrez IDs?
ALIAS ENTREZID
NUDT10 53343
NUDT10 170685
Is this usual to have many to many mapping? Is there a way to give only one to one mapping?
Thank you!
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https://www.ncbi.nlm.nih.gov/gene/?term=NUDT10 In this case 'NUDT10' one gene symbol can have many alias, even on different chromosomes (chrX, chr4). How should the decision be made?
53343is NUDT9170685is NUDT10Yes, but NUDT10 is also the alias of 'NUDT9'. Also the command showed the same:
Can you not use the primary gene name (instead of the alias)?
Yes I think you should be using "SYMBOL" instead of "ALIAS"
Thank you, that worked!