Thanks a lot. Could I run the GO annotation by myself?
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jiang_lan •
How to do GO annotation with non-model animal
I don't know choose which tool to annotate with non-model animal, I tried the R package "AnnotationHub", however, the GO result is empty with NA, please help me! Thanks a lot.
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Biostar
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jiang_lan •
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jiang_lan •
2 answers
The way to do this is to transfer annotations by orthology, i.e. use annotations from orthologs in well-annotated species.
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Jean-Karim Heriche
What do you mean by 'run the GO annotation' ? You identify orthologs of your gene G in species X then take the GO terms associated with the orthologs of G in X and assign them to G. You could use more than one species to transfer annnotations in this way.
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Jean-Karim Heriche
Hello, You can easily annotate GO functions for your own proteomes online using OMA: https://omabrowser.org/oma/functions/
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Natasha Glover •
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