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OMA Warning Unknown character U

Hello,

I just initiated an OMA run, and I get the following warning:

WARNING: Unknown character: U (in gi|1035271291|ref|XP_008310584.2| PREDICTED: selenoprotein O [Cynoglossus semilaevis], CYSEM pos 689) --> X

for almost all sequences. Can somebody tell me why U is an unknown character and how can I avoid this error?

oma orthologs

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1 answer

https://ru.wikipedia.org/wiki/%D0%90%D0%BC%D0%B8%D0%BD%D0%BE%D0%BA%D0%B8%D1%81%D0%BB%D0%BE%D1%82%D1%8B

U - selenocystein. As far as I know, OMA recognizes only 20 aminoacids. You have to replace U to cystein (C) in protein sequences.

https://ru.wikipedia.org/wiki/%D0%A1%D0%B5%D0%BB%D0%B5%D0%BD%D0%BE%D1%86%D0%B8%D1%81%D1%82%D0%B5%D0%B8%D0%BD

Thank you, I didn't notice I gave a Russian one.

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