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Different pubmed search using R

Hi all, I was trying to multiple different search using R.I was trying the RISmed package where i used c to concantenate my search terms as shown below: search_topic<-c("KRAS AND MEK inhibitor","BRAF AND BRAF inhibitors") but when i try to run it,I get the following error: Error in file(con, "r") : cannot open the connection to 'https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esearch.

Is there a way to tackle this error? If not, can someone direct me towards the right package where I do multiple different pubmed search.

Thank you!

r pubmed

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