STAR vs STAR-fusion · Biostar

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STAR vs STAR-fusion

Hello,

I am reading the STAR manual and I came across the publication for STAR-fusion. I could not understand how different they are from each other. Could someone help me understand the difference?

Thank you in advance.

star-fusion star

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updated 3.4 years ago by Ram

• written 8.9 years ago by KVC_bioinfo

1 answer

STAR aligner is a splice aware aligner that aligns junction reads using a guide GTF. STAR-fusion allows identification of fusion transcripts. In many cases you get fusion transcripts due to chromosomal translocation (cancer) or trans-splicing etc. Other splice aware aligners (Tophat-Fusion) also have fusion engine for same purpose.

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written 8.9 years ago by Satyajeet Khare

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