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comparing two illumina genotypes report

Hi All,

I have two final illumina reports from bead chip experiment (300,000 SNPs). Ideally genotypes of these two samples should be identical. How can I compare between the genotypes of the two samples to see if they are really identical or there are some mismatches?

The files look like this;

CHROM   POS             ID              Sample_ID           Allele1  Allele2   GC_Score

3       183635768       rs1000002       200638550003_R01C01     A       G       0.8902

3       98342907        rs1000003       200638550003_R01C01     A       G       0.9351

4       103374154       rs10000030      200638550003_R01C01     A       G       0.7764

4       38924330        rs10000037      200638550003_R01C01     G       G       0.929

4       165621955       rs10000041      200638550003_R01C01     A       A       0.8957

2       237752054       rs1000007       200638550003_R01C01     A       G       0.9491

Thanks Tarek

gtc_files

1 answer

How about converting the files to VCF then using one of many VCF comparison tools?

Hi Kronenberg, Thanks for the reply! What would be the best way to convert illumina genotype report to VCF?

Regards Tarek

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