How to confirm exon shuffling in a gene?
Hi everyone, I'm trying to confirm that the sequence of a novel gene is derived by exon shuffling between several different genes. I have the promoter sequence, gene sequence, and mRNA (with defined exon/intro boundaries). I've tried performing several database searches with the sequences, but each search produces a set of different unrelated hits. How would one go about using this info to confirm the exon shuffling hypothesis? Any tips are appreciated. Thanks!
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Hello mj2000!
It appears that your post has been cross-posted to another site: https://bioinformatics.stackexchange.com/questions/2323/how-to-confirm-exon-shuffling-in-a-gene
This is typically not recommended as it runs the risk of annoying people in both communities.
Hello mj2000!
It appears that your post has been cross-posted to another site: Reddit too https://www.reddit.com/r/bioinformatics/comments/6udxef/how_to_confirm_a_gene_is_derived_by_exon/?st=j6hk7ejm&sh=885530b6
This is typically not recommended as it runs the risk of annoying people in both communities.