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SingleCell RNaseq normalisation

Hi I am analysing singleCell RNAseq data, in one batch of cells I have more spike-in than in the others (a different concentration of spike_in has been added to the RNA). I was wondering what is the best procedure to normalise the data to be able to integrete these cells in the analysis Thank you Nadia

singlecell rnaseq spike_in normalisation

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