I would like to find the orthologs/inparalogs for a set of human genes wide range of species concerning evolutionary distance: bacteria/archaea, fungi, plants...
Initially I've thought of a pairwise method such as Inparanoid, but its code performance is not good enough for a large number of proteomes (unless there's another version suitable for MPI or multithreading). I could use other methods based on groups of orthologs (OGs), but I am not quite interested in OGs, since I want to map human genes to distant and closer species/groups.
Any suggestions are very wellcome!
Thanks a lot in advance