compare motif enrichment across 3 different genomic regions
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7.1 years ago

I have 3 different groups of genomic regions, the same size (500bp) but different number of intervals (1000,1500,2000). I want to do motif enrichment and compare the results. I have run ame with 5000 random genomic regions as background (I used the same bg file for all runs). My question is that: are the results (q-valuess) directly comarable accross the three different regions? e.g. Can I directly comare the q-value for a TF like OCT4 among these regions? or I can not becuase of different number of intervals? shall I somehow take that into account? would you please help me and tell me how to do that?

motif motif enrichment ChIP-Seq • 1.3k views
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