The bed12 format
Hi, I just came across bed12 format for the first time http://bedtools.readthedocs.io/en/latest/content/general-usage.html
I didn't quite understand what "thickStart" and "thickEnd" mean - is it simply a representation of the visual line that would be drawn?
Thanks,
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I didn't quite understand what "thickStart" and "thickEnd" mean - is it simply a representation of the visual line that would be drawn?
You are right. It is useful when you need to represent bed intervals for genes with introns/exons/cds/UTRs like on the image below where the thick lines represent cds.

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You can get answer from What Does Thickstart (Col 7) Or Thickend (Col 8) Mean In A Bed File?