First of all, thank you very much for your detail answer!! It is very helpful and appreciate!
This is a bit fuzzy. Paired-end (PE) data has two files (with R1 and R2 in the name to indicate the files containing reads from two ends of fragments sequenced). I am not sure why there is single-end (SE) data unless the samples were separately sequenced separately.
I agree, that is why I am a bit perplex with the SE data. The forward and reverse are indeed annotated R1 and R2. I will try to have more detail on the SE files.
There is nothing special to indicate the sequencing would be MiSeq unless these are 150+ bp long reads, lengths of up to 300 bp only possible on MiSeq. It is possible to identify data as being from MiSeq by looking at the barcode of the flowcell (which should be in all read headers).
I have a document which seems to be describing the features of the files, but it is very unclear to me (that is why I end up asking here) but one of the thing I understood was this difference, and it is noted in the name of the files (which I guess is also visible in the read headers).
These could be mate-pair libraries with longer inserts. There may be two insert lengths.
Ok! I will check that! Thank you very much for the clue!
And thank you very much for the total answer one more time, it really helps me to clarify a bit things! :)