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TCGA Illumina Methylation 27 array data normalization

Hi: I'm new to Bioinformatics, and I started to browse the TCGA database for methylation array files. I found some files from Illumina Methylation 27 that I pretended to use for analysis. My question is about the normalisation of the data: Are values across different files comparable? and if not, what strategy should I use for normalising?

Thanks

Juan

methylation r tcga illumina
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updated by Shicheng Guo Shicheng Guo • written by Nopstoc • Nopstoc

1 answer

Computational tools for DNA methylation: too many existed normalization method could be applied in existed R packages.

See: Gallery: Computational tools for DNA methylation

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written by Shicheng Guo Shicheng Guo

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