hi every one
i get millions snp from NGS data (camel genome), now i would to annotate these variants
What way to do this, you recommend?
1 answer
Look at these sources, they may be helpful.
Snpdat: easy and rapid annotation of results from de novo snp discovery projects for model and non-model organisms.
https://www.ncbi.nlm.nih.gov/pubmed/23390980
These authors (above) compare model and non-model organisms in terms of SNP-findings.
These papers below are about some camel research:
Genome sequences of wild and domestic bactrian camels
http://sci-hub.cc/10.1038/ncomms2192#
Identification of SNPs and their validation in camel (Camelus bactrianus and Camelus dromedarius)
http://iosrjournals.org/iosr-javs/papers/vol7-issue2/Version-2/J07226570.pdf
Sequencing, Analysis, and Annotation of Expressed Sequence Tags for Camelus dromedarius
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0010720
Estimating the Population Mutation Rate from a de novo Assembled Bactrian Camel Genome and Cross-Species
Comparison with Dromedary ESTs
http://jhered.oxfordjournals.org/content/early/2014/06/05/jhered.est005.full.pdf
The de novo genome assembly and annotation of a female domestic dromedary of North African origin
http://onlinelibrary.wiley.com/doi/10.1111/1755-0998.12443/pdf
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Could be helpful if you mention the aim of your analysis and the type of annotation you aim to obtain.
i want to identify genic and intergenic snp, synonymous and non-synonymous snp and other annotation like this