I want to analyze missense mutations in my gene. I choose my missense SNPs via ensemble website (GRCh37) with 0-0.05 and 0.92-1 scores for SIFT and PolyPhen2 respectively. But the problem is when I search that selected SNP IDs (filtered just for dbSNP) directly in SIFT website, none of them are being recognized. Could anybody explain what should I do?
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In which format did you put those SNPs in SIFT? In case of doubt, read the documentation on which formats are accepted: http://sift.jcvi.org/www/chr_coords_example.html