Hi! I have two datasets of proteins, each of them is a collection of clusterized proteins obtained using OrthoMCL. What I'd like to know is this: If I make a MSA among the members of each cluster in each dataset, can I infer from them (by making an average between all the clusters) if dataset A evolved faster or slower in comparison with dataset B? How would you do it? I was reading on a review that the alignment percentage could be a good metric, but is it true?