How can I be sure, that my solved protein structure has a new fold? · Biostar

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How can I be sure, that my solved protein structure has a new fold?

I have tried several webs (CATH, Dali, ProFunc, Pfam) to classify my structure into some fold / superfamily, but they did not find anything (Dali, Pfam), or really weak hits (Q-score < 0.16). The question is, how to demonstrate that the structure has a new fold? I have solved the structure thoroughly by NMR and we have another checks in agreement with the structure.

new fold protein structure dali cath

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written 9.8 years ago by 236585 •

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