Homology Modeling without high sequence identity
Dear all,
I'm quite new into bioinformatics and I want to make a homology model of a protein, but the templates and my protein have only around 10 to 20% sequence identity, so sequence alignment is not that easy. Nevertheless, the structural fold is very similar. What is the best way to make a homology model? Can you recommand a certain software for this task?
Thanks for all answers!
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