I want to index a reference then I would query different k-mers of different length in it. I think fm-index would be the best for it. But could you suggest me the best API that is usually used by bioinformaticians for fm-indexing?

Till now, I found SDSL as the best which is a general tool. Is there any other efficient tool? or is there any other tool made efficiently for bioinformatics?

Thanks in advance.