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value of crit.pca.distances value for PcaHubert function of rrcov package for outlier removal in gene expression data

Hello everyone,

I have around 450 sample, which i think is too much for differential expression calculation. I am using PcaHubert function for outlier removal. There is a parameter named crit.pca.distances which is some kinds of distance.

can somebody explain this parameter to a biologist and what should be the good value to use for this parameter?

Thank You.

expression outlier removal

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