I'm new to packages like 'circos' and 'circlize' and cannot figure out how to create a simple chord diagram showing amino acid changes in missense mutations. The circle is divided into two equal arcs (reference and altered) and each of them should contain three categories (polar, hydrophobic, charged).

Here's a portion of the actual data

REF,ALT
polar,polar
charged,polar
polar,hydrophobic
charged,polar
charged,polar
charged,polar
hydrophobic,polar
charged,polar