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searching short peptide sequences against a large database

Hello,

I want to search a set of local databases with short peptide queries. I am interested in finding sequences with high sequence similarity. Which tools are optimal for this? I have noticed that the usual BLAST settings aren't optimal for finding matches to the short queries within larger databases. I have little bioinformatics experience, so any advice is highly appreciated:)

blast alignment sequence peptide

2 answers

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