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RNA intra-condition paralogue expression

Hi, I am working in the expression of duplicate gene inside a same condition (same experiment). for example does all the paralogue are express? or just several? are some more express than other? I wonder if in this case comparing set of gene inside a condition fpkm or tmp value would be sufficient. If not do you know if I could use deseq2 or edgeR (with reads count) in such experimental design?

rna-seq

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